abPOA is an extended version of Partial Order Alignment (POA) that performs adaptive banded dynamic programming (DP) with an SIMD implementation. abPOA can perform multiple sequence alignment (MSA) on a set of input sequences and generate a consensus sequence by applying the heaviest bundling algorithm to the final alignment graph.
abPOA can generate high-quality consensus sequences from error-prone long reads and offer significant speed improvement over existing tools.
abPOA supports three alignment modes (global, local, extension) and flexible scoring schemes that allow linear, affine and convex gap penalties. It right now supports SSE2/SSE4.1/AVX2 vectorization.
This is free and open source software.
Key Features
- Cross-platform support – runs under Linux and macOS.
Website: github.com/yangao07/abPOA
Support:
Developer: Yan Gao
License: MIT License
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