Bioinformatics

samtools – manipulate next-generation sequencing data

samtools is a suite of tools written in C using HTSlib for manipulating next-generation sequencing data.

It forms part of the coordinated Samtools project alongside HTSlib and BCFtools, and provides utilities for working with SAM, BAM, and CRAM alignment files. The software is widely used in genomics workflows for file conversion, sorting, querying, indexing, statistics, and related sequence-data processing tasks.

This is free and open source software.

Key Features

  • Provides tools for manipulating next-generation sequencing data.
  • Works with SAM, BAM, and CRAM alignment file formats.
  • Supports file format conversion and data manipulation tasks.
  • Includes tools for sorting and querying sequencing data files.
  • Offers indexing functionality for alignment files.
  • Provides statistical and pileup-related tools for sequence data analysis.
  • Builds on HTSlib as part of the coordinated Samtools software suite.

Website: github.com/samtools/samtools
Support:
Developer: Genome Research Ltd
License: MIT/Expat License

samtoolsis written in C. Learn C with our recommended free books and free tutorials.


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Read our verdict in the software roundup.


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