Bioinformatics

Jalview – multiple sequence alignment editing, visualisation and analysis

Jalview is a cross-platform program for multiple sequence alignment editing, visualisation and analysis. Use it to view and edit sequence alignments, analyse them with phylogenetic trees and principal components analysis (PCA) plots and explore molecular structures and annotation.

The Jalview Desktop is an application you can launch from the web or install locally. It is designed for the kind of in-depth sequence analysis necessary when exploring new protein or RNA sequence families to understand how their sequence relates to structure and function.

The Desktop can access sequence, alignment, 3D structure and annotation databases, and web services for multiple alignment, protein disorder and secondary structure prediction and functional analysis.

Jalview is able to link views of 3D structures to multiple sequence alignments. Jmol is integrated with Jalview for this, but you can also configure Jalview to use Chimera, ChimeraX and Pymol for 3D structure visualisation.

Alignments can also be linked to RNA secondary structure visualisations with VARNA, also included in the Jalview Desktop.

Website: www.jalview.org
Support:
Developer: Managed by The Barton Group, University of Dundee, UK
License: GNU General Public License v3.0

Jalview in action

Jalview is written in Java. Learn Java with our recommended free books and free tutorials.

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