Bioinformatics

Integrative Genomics Viewer – high-performance visualization tool for interactive exploration of large, integrated genomic datasets

The Integrative Genomics Viewer (IGV) is a high-performance visualization tool for interactive exploration of large, integrated genomic datasets. It supports a wide variety of data types, including array-based and next-generation sequence data, and genomic annotations.

Navigation through a dataset is similar to Google Maps, allowing the user to zoom and pan seamlessly across the genome at any level of detail from whole-genome to base pair.

IGV’s scalable architecture makes it well suited for genome-wide exploration of next-generation sequencing (NGS) datasets, including both basic aligned read data as well as derived results, such as read coverage.

Key Features

  • Flexible integration of a wide range of genomic data types including aligned sequence reads, mutations, copy number, RNAi screens, gene expression, methylation, and genomic annotation.
  • Use of efficient, multi-resolution file formats to enable real-time exploration of arbitrarily large datasets over all resolution scales, while consuming minimal resources on the client computer.
  • Supports concurrent visualization of diverse data types across hundreds, and up to thousands of samples, and correlation of these integrated datasets with clinical and phenotypic variables
  • Datasets can be loaded from local or remote sources, including cloud-based resources, enabling investigators to view their own genomic datasets alongside publicly available data from, for example, The Cancer Genome Atlas (TCGA, 1000 Genomes (www.1000genomes.org/), and ENCODE (www.genome.gov/10005107) projects. In addition, IGV allows collaborators to load and share data locally or remotely over the Web.
  • Cross-platform support – runs under Linux, Mac OS X, Windows, and any other operating system that supports Java 8 or 11.

Website: igv.org/doc/desktop
Support: User Guide, GitHub Code Repository
Developer: Broad Institute and Regents of the University of California
License: MIT License

IGV

IGV is written in Java. Learn Java with our recommended free books and free tutorials.


Related Software

Bioinformatics Tools
BioconductorAnalysis and comprehension of high-throughput genomic data
BiopythonTools for biological computation written in Python
UGENESet of integrated bioinformatics software
BioPerlPerl tools for computational molecular biology
GROMACSVersatile package to perform molecular dynamics
IGVHigh-performance visualization genome browser tool
GATKGenomic analysis toolkit focused on variant discovery
BioJavaProvides Java tools for processing biological data
InterMineIntegrate biological data sources
bedtoolsPowerful toolset for genome arithmetic
EMBOSSThe European Molecular Biology Open Software Suite
BLASTAlgorithm for comparing primary biological sequence information
GalaxyWeb-based platform for data-intensive computational research
minimap2Versatile sequence alignment program
JalviewMultiple sequence alignment editing, visualisation and analysis
samtoolsManipulate next-generation sequencing data
BCFtoolsVariant calling and manipulating files in the Variant Call Format
FastQCQuality control tool for high throughput sequence data
SPAdesVersatile toolkit for assembling and analysing sequencing data
GenomeToolsCollection of bioinformatics tools
AliViewAlignment viewer and editor
mothurAnalyze microbial communities
BandageVisualising de novo assembly graphs
craminoBAM/CRAM quality evaluation
abPOAAdaptive banded Partial Order Alignment
Taverna WorkbenchFor designing and executing bioinformatics workflows
geWorkbenchSoftware platform for integrated genomic data analysis
BioclipseRich-client platform chemistry and biology workbench

Read our verdict in the software roundup.

Desktop Genome Browsers
IGVHigh-performance visualization genome browser tool
IGBIntegrated Genome Browser
JBrowseFast, scalable genome browser
TabletGraphical viewer for sequence assemblies and alignments
UGENESet of integrated bioinformatics software
ArtemisGenome viewer and annotation tool
ApolloInstantaneous, collaborative genomic annotation editor
CutePeaksCross platform Sanger Trace file viewer
Genome WorkbenchIntegrated tools for studying and analyzing genetic data

Read our verdict in the software roundup.


Best Free and Open Source Software Explore our comprehensive directory of recommended free and open source software. Our carefully curated collection spans every major software category.

This directory is part of our ongoing series of informative articles for Linux enthusiasts. It features hundreds of detailed reviews, along with open source alternatives to proprietary solutions from major corporations such as Google, Microsoft, Apple, Adobe, IBM, Cisco, Oracle, and Autodesk.

You’ll also find interesting projects to try, hardware coverage, free programming books and tutorials, and much more.

Discovered a useful open source Linux program that we haven’t covered yet? Let us know by completing this form.
Subscribe
Notify of
guest
0 Comments
Oldest
Newest Most Voted
Inline Feedbacks
View all comments