minimap2 is a versatile sequence alignment program for genomic and spliced nucleotide sequences.
This software aligns DNA or mRNA sequences against a large reference database and is designed for mapping, overlap detection, splice-aware alignment, and assembly or genome alignment tasks.
This is free and open source software.
Key Features
- Aligns DNA or mRNA sequences against a large reference database.
- Supports mapping of genomic long reads from PacBio and Oxford Nanopore technologies.
- Finds overlaps between long reads.
- Provides splice-aware alignment for long reads and cDNA against a reference genome.
- Supports alignment of full-length cDNA or mRNA sequences against a reference genome.
- Supports alignment of genomic short reads from Illumina platforms.
- Supports assembly-to-reference alignment.
- Supports full-genome alignment between closely related species.
- Outputs approximate mappings in PAF format.
- Outputs base-level alignments in SAM format.
Website: github.com/lh3/minimap2
Support:
Developer: Heng Li
License: MIT License
minimap2 is written in C. Learn C with our recommended free books and free tutorials.
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Read our verdict in the software roundup.
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