Dc-qt is a DirectConnect client based on DC++ for Linux and MacOS X, with a separate backend / gui architecture. It is written in C++ and comes with a Qt GUI.
Dolda Connect supports most of the latest features of the DC protocol. It runs in client/server mode with a well defined protocol, allowing extensibility, flexibility, and multiple detachable user interfaces. It also has an optional multi-user mode.
EiskaltDC++ is a cross-platform program that uses the Direct Connect and ADC protocols. It is compatible with DC++, FlylinkDC++, LinuxDC++ and other DC clients. EiskaltDC++ also interoperates with all common DC hub software.
Linux DC++ is a project to port the DC++ direct connect client to Linux or any POSIX-compliant Unix.
microdc is a command-line based Direct Connect client that uses GNU Readline for user interaction. microdc is developed from ground up and does not depend on any other programs. It is designed to be user friendly and simple to use.
ncdc is a modern and lightweight Direct Connect client with a friendly text-mode interface.
Open DC Hub
Open DC Hub is a Unix/Linux version of the hub software for the Direct Connect network. Direct Connect is a file sharing network made up by hubs, to which clients can connect.
QuickDC is a clone of Neo-Modus' DirectConnect for Linux/Unix. A peer-to-peer file sharing utility, written in C++ using Trolltech's Qt library. Aiming to be fast, secure, portable and customizable.
SimpleDC++ is a client for DC++ networks that supports multi-threaded downloading.
Valknut/DCLib is a Direct Connect file sharing client.