ChemSpotlight is a Spotlight metadata importer plugin for Mac OS X 10.4 Tiger, which reads common chemical file formats (MDL .mol, .mdl, .sd, .sdf, Tripos .mol2, Protein Data Bank .pdb, Chemical Markup Language .cml, and XYZ) using the Open Babel chemistry library. It is provided as a Universal Binary for PowerPC and Intel, for optimized performance on both.
ChromeCalc is a stylish and fully featured Calculator for Mac OS X. Features include the ability to use different bases (Base-2, Base-8, Base-10 and Base-16), a Recent Calculations drawer for viewing your recent calculations, Internet Checking for new versions of the App and the ability to save your recent calculations to a text file.
Distillation Designer is a simple binary distillation modelling tool using the McCabe-Thiele method. It will be of use to students studying Chemical Engineering.
iBabel gives access to chemical file conversion, sub-structure and similarity searching, overlays, sorting and manipulation of lists of compounds, also include structure viewing capabilities, using JMOLand JChempaint (Included in application bundle).
MacMolPlt is a Chemistry visualization tool that can be used to build molecules with an integrated graphical model builder, create input files for the GAMESS computational chemistry program, and then visualize the results of computational chemistry runs. Features include a high-quality 3D display, animations of normal modes and reaction sequences and output to a variety of formats including high-quality images and QuickTime and Flash movies.
Mercury offers a comprehensive range of tools for structure visualisation and the exploration of crystal packing.
(commercial) an interactive Chemistry Lab Simulation
Periodic Table X
(commercial) a versatile chemistry reference tool for your Macintosh that takes the periodic table beyond the simple paper periodic table found in so many textbooks and classrooms
SpotSmart is a perl script to enhance ChemSpotlight with substructure searching.